The short answer
Based on available data, the Infiniti QX50 comes out ahead of the Lexus NX on power. Check the specs table and owner sentiment below for the full comparison before deciding between the two. Both are covered by real owner reports on CarWizz.
Overall
Sentiment is sharply divided by generation, with a clear consensus that the 2016-2017 (first-generation) models are highly regarded, while the 2019+ (second-generation) models are widely criticized. The first-generation QX50, equipped with the 3.7L V6 and a 7-speed automatic transmission, is consistently praised for its powerful, reliable engine, sporty handling derived from the FM platform shared with the 370Z and G37, and strong value as a used vehicle. Owner satisfaction for these models is very high, with reports of trouble-free ownership up to high mileages.
Best version to buy
The 2016-2017 QX50 with the 3.7L V6 engine, RWD or AWD, and the 7-speed automatic transmission is overwhelmingly recommended as the best version. Specific praise is given to the 2016 model year, which received a stretched wheelbase for increased rear legroom.
Known issues
Overall
Mixed to positive sentiment, heavily dependent on model year and powertrain. The vehicle is widely praised for its exceptional long-term reliability, with the 2015-2021 generation specifically highlighted as "bulletproof." Owners of the post-2022 redesign appreciate the updated technology, smoother ride quality, quieter cabin, and refined interior. However, significant criticism is directed at specific, recurring issues: a very frequent and severe 12V battery drain problem in NX 350h hybrid models, leading to repeated dead batteries; various electrical gremlins and rattles in multiple generations; and a powertrain in earlier turbo models (200t/300) described as underwhelming, with sluggish acceleration and a requirement for premium fuel.
Best version to buy
Insufficient owner data available to declare a single "best" trim or version. Feedback is split by powertrain: the hybrid (350h) is favored for its fuel efficiency and smoothness, but is plagued by battery issues.
Known issues
The verdict
The Infiniti QX50 is the better choice for most buyers.
It has more power on its best-equipped version than the Lexus NX, based on the data above. If efficiency matters more to you than outright power, the Lexus NX is worth a closer look instead.
Common problems by model year
Other comparisons
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Owner reports show similar reliability sentiment for the Infiniti QX50 and the Lexus NX. Check the known issues listed above for specific differences between the two.
Data on family-specific factors like cargo space is limited for one or both models, but based on available reports, both are positioned as practical daily drivers. Check the specs table above for seating and body type.
The EPA rates the 2025 Infiniti QX50 at 25–26 mpg combined and the 2026 Lexus NX at 24–40 mpg, depending on the version.
Exact maintenance costs aren't in our data, but reliability signals above are the closest proxy: fewer reported issues generally means lower repair costs over time.