The short answer
Based on available data, the Cadillac CT6 comes out ahead of the Lexus LS on power. Check the specs table and owner sentiment below for the full comparison before deciding between the two. Both are covered by real owner reports on CarWizz.
Overall
Mixed sentiment with a clear divide between appreciation for the vehicle's core attributes and significant concerns over reliability and long-term viability. The CT6 is widely praised for its driving dynamics, particularly on the advanced Omega platform, which is noted for excellent handling and weight transfer. It is considered a cutting-edge luxury machine offering strong value, especially when purchased used, with powerful engine options (notably the 3.0L Twin-Turbo V6 and the rare 4.2L Twin-Turbo "Blackwing" V8) providing substantial performance.
Best version to buy
Insufficient owner data available to declare a consensus "best" trim. The high-performance CT6-V with the 4.2L Twin-Turbo V8 (Blackwing) is mentioned as a rare, fun halo car but is universally flagged for severe reliability concerns and future parts scarcity.
Known issues
Overall
The sentiment is overwhelmingly positive, characterized by deep owner loyalty and satisfaction with the vehicle's core mission of providing unparalleled long-term comfort, refinement, and reliability. The LS is consistently described as a benchmark for a "decade-plus" ownership experience with minimal drama, offering a sense of solidity, quietness, and effortless power that makes other vehicles feel "a bit cheap by comparison." While there is strong consensus on its supreme comfort and build quality, nuanced criticisms exist regarding specific model years and components. The LS460 (2007-2017) is praised for its bulletproof V8 but noted for expensive wear items like control arms and air suspension.
Best version to buy
For the LS460 generation, later model years (e.g., 2017) are implied to be more refined and reliable than early first-year models (e.g., 2007), which are described as "Toyota's bastard child for reliability." For the current LS500 generation, the LS500h AWD with the "Teammate" advanced driver-assist system is mentioned as a highly capable but rare and expensive configuration. There is no single trim consensus, but the underlying recommendation is to seek well-maintained examples with full service histories, regardless of specific year or trim.
Known issues
The verdict
The Lexus LS is the better choice for most buyers.
It has stronger reliability sentiment in owner reports than the Cadillac CT6, based on the data above. If the specific known issues on the Lexus LS are a dealbreaker, the Cadillac CT6 is worth a closer look instead.
Common problems by model year
Other comparisons
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Owner reports lean more positive on reliability for the Lexus LS than the Cadillac CT6. See the known issues comparison above for the specific concerns owners report on each.
The Cadillac CT6 seats more passengers than the Lexus LS on its catalogued best-equipped version. Body type also differs: the Cadillac CT6 is classed as a Sedan, the Lexus LS as a Sedan.
The EPA rates the 2020 Cadillac CT6 at 17–21 mpg combined and the 2026 Lexus LS at 21 mpg, depending on the version.
Exact maintenance costs aren't in our data, but owner reports mention cost-related concerns more often for the Cadillac CT6 than the Lexus LS. See the known issues comparison above.