The short answer
Based on available data, the Lexus GX comes out ahead of the Infiniti QX60 on power and long-term reliability. Check the specs table and owner sentiment below for the full comparison before deciding between the two. Both are covered by real owner reports on CarWizz.
Overall
Sentiment is sharply divided by model year and generation, with reliability being the dominant theme. For the first-generation models (approximately 2014-2021), sentiment is overwhelmingly negative due to widespread, severe transmission failures associated with the CVT (Continuously Variable Transmission). These failures are described as catastrophic, often occurring between 20,000 and 120,000 miles, with repair costs equaling or exceeding the vehicle's value.
Best version to buy
For the second generation (2022+), the Autograph trim is mentioned as being well-equipped and desirable. For the first generation, no specific trim is recommended due to the overarching transmission concerns.
Known issues
Overall
Sentiment is sharply divided by generation. The previous-generation GX 460 (model years up to 2023) is overwhelmingly praised for its legendary reliability, proven V8 powertrain, comfortable and durable luxury, and high long-term value. Owner feedback describes it as a "bulletproof," over-engineered vehicle that benefits from decades of refinement, with a 10-year cost of repairs reportedly half that of competitors.
Best version to buy
For the GX 460 generation, the final model year (2023) is specifically highlighted as the "one to have" due to receiving the latest updates and a newer infotainment system with Apple CarPlay/Android Auto. The Luxury trim is highly recommended for its adjustable ride control (Comfort/Sport settings), which owners find invaluable for tuning ride quality on different road surfaces.
Known issues
The verdict
The Lexus GX is the better choice for most buyers.
It has stronger reliability sentiment in owner reports than the Infiniti QX60, based on the data above. If the specific known issues on the Lexus GX are a dealbreaker, the Infiniti QX60 is worth a closer look instead.
Common problems by model year
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Owner reports lean more positive on reliability for the Lexus GX than the Infiniti QX60. See the known issues comparison above for the specific concerns owners report on each.
The Infiniti QX60 seats more passengers than the Lexus GX on its catalogued best-equipped version. Body type also differs: the Infiniti QX60 is classed as a SUV, the Lexus GX as a SUV.
The EPA rates the 2027 Infiniti QX60 at 24 mpg combined and the 2026 Lexus GX at 17 mpg, depending on the version.
Exact maintenance costs aren't in our data, but owner reports mention cost-related concerns more often for the Infiniti QX60 than the Lexus GX. See the known issues comparison above.