The short answer
The Acura MDX offers power, while the Toyota Highlander excels at fuel economy instead. Choose the Acura MDX if you prioritize power in daily driving, or the Toyota Highlander if fuel economy matters more for your needs. Both are covered by real owner reports on CarWizz.
Overall
Overwhelmingly positive sentiment for first-generation model, widely regarded as groundbreaking luxury three-row SUV establishing segment template and Honda reliability reputation. Praised extensively for exceptional longevity with examples routinely exceeding 250,000-300,000 miles (402,000-483,000 km), comfortable ride quality, spacious three-row seating accommodating adults, powerful 3.5L V6 engine (240-265 hp depending on year), and low maintenance costs typical of Honda engineering. Owners report emotional attachments spanning 15-20+ years and multiple hundred thousand miles, describing MDX as "best vehicle ever owned" and "family member." However, criticism includes outdated technology by modern standards (no Bluetooth, basic infotainment in early years), thirsty fuel consumption (16-19 MPG combined), transmission issues affecting some high-mileage examples beyond 200,000 miles, and typical Honda third-row tightness for adults.
Best version to buy
3.5L V6 with Technology Package (2004-2006) The 2004-2006 model years preferred for revised 265 hp engine (versus 240 hp 2001-2003), improved transmission calibration addressing early issues, and Technology Package adding navigation, rear entertainment, premium audio. The SH-AWD (Super Handling All-Wheel Drive) system standard across all trims providing excellent winter traction and handling dynamics. 2005-2006 final years represent most refined iteration before second-generation redesign.
Known issues
Overall
Sentiment is mixed and heavily dependent on model year and powertrain. The Highlander is widely recognized as a reliable, practical, and comfortable family SUV, praised for its solid build quality, good ride comfort, and strong resale value. Long-term owners of older generations, particularly those with V6 engines and 6-speed automatics, report exceptional reliability with minimal issues.
Best version to buy
For gas models, the 2015-2016 model years are very frequently recommended as the peak of reliability, featuring a proven V6 and 6-speed automatic. For newer models, the Hybrid variant is overwhelmingly recommended over the gas-only version due to its reliable eCVT transmission, superior fuel economy, and avoidance of the problematic 8-speed automatic.
Known issues
The verdict
The Toyota Highlander is the better choice for most buyers.
It has better fuel economy on its best-equipped version than the Acura MDX, based on the data above. If power matters more to you than running costs, the Acura MDX is worth a closer look instead.
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Which is more reliable, the Acura MDX or the Toyota Highlander?
Owner reports show similar reliability sentiment for the Acura MDX and the Toyota Highlander. Check the known issues listed above for specific differences between the two.
Which is better for families, the Acura MDX or the Toyota Highlander?
The Toyota Highlander seats more passengers than the Acura MDX on its catalogued best-equipped version. Body type also differs: the Acura MDX is classed as a SUV, the Toyota Highlander as a SUV.
Which has better fuel economy, the Acura MDX or the Toyota Highlander?
The Toyota Highlander is more fuel-efficient on paper: 10.2 L/100km combined versus 12.4 L/100km for the Acura MDX, based on the best-equipped catalogued version of each.
Which is cheaper to maintain, the Acura MDX or the Toyota Highlander?
Exact maintenance costs aren't in our data, but owner reports mention cost-related concerns more often for the Toyota Highlander than the Acura MDX. See the known issues comparison above.